![]() Using a database of genomic information for people in Turkey, the researchers identified people who carried the mutation in CRY1. In the new study, Patke's team confirmed CRY1 genetic mutation's link to delayed sleep phase disorder by looking for the mutation among the woman's extended family, and in other population samples. The mutation is a single-point mutation in the CRY1 gene, meaning just one "letter" in its genetic instructions is off. In sequencing her genes, the researchers identified the CRY1 mutation. In this isolation, the woman settled into a rhythm that stretched about 1 hour longer than the typical 24-hour circadian cycle, and her sleep was fragmented, Patke said. "Then we told her to live on her own timeline and to eat and sleep according to what her body told her to do." "It didn't have windows, TV or internet," Patke said. ![]() She was placed in an apartment for two weeks that was isolated from all time cues. Patke's team and other researchers analyzed the woman's natural sleep patterns. ![]() woman who had come to a sleep clinic after a long struggle with her late sleep cycle. Patke and her colleagues first identified the DSPD-linked mutation seven years ago, in a 46-year-old U.S. "But someone like a surgeon who has to be in the OR in the early morning – that's not compatible." "A person like a bartender, for example, might not experience any problem with the delayed sleep cycle," Patke told Live Science. Most people are hard-wired to a 24-hour clock, but up to 10 percent of peoplewith DSPD follow an internal clock that runs on a longer loop. In people, it dictates when one feels tired, hungry or awake. Since sleep is essential for optimal performance, health, and well-being, it's important to develop strategies to get better rest," says Boivin, who is also the Director of the Centre for Study and Treatment of Circadian Rhythms at The Douglas Research Centre.Īs next steps, the researchers hope to study the impact of chronotype and shift work on other health outcomes.The circadian clock is an internal rhythm that guides nearly all life on Earth. "People involved in shift work experience an increased risk of sleep disturbances and fragmented sleep periods. Such strategies could include work schedules that consider chronobiological principles. The findings could help design strategies to improve sleep in workers with atypical schedules, the researchers say. Generally, early risers slept less after night shifts compared to night owls - but they also took more naps prior to their night shifts, so their total daily sleep was similar. While shift workers take naps to reduce the effect of their irregular schedules on their sleep, the researchers found this behaviour was more prominent during night shifts in early risers. On average early risers sleep 1.1 hours longer on morning shifts, while night owls sleep two hours longer on evening shifts," says co-author Laura Kervezee, a former Postdoctoral Fellow at The Douglas Research Centre affiliated with McGill University. "Our results suggest that the effect of chronotype on sleep duration and napping behavior depends on the shift type. For close to a month, the officers wore a watch-like device, allowing researchers to measure their sleep. To investigate this relationship, the researchers tracked 74 police officers as they worked their usual shifts. Their study published in Sleep is the first to examine the relationship between chronotype and sleep behaviour in shift workers during morning, evening, and night shifts. Boivin, a Professor in the Department of Psychiatry at McGill University. This preference, called chronotype, is modulated by our circadian system - each person's unique internal timekeeper," says lead author Diane B. ![]() "Some people seem to be hardwired to sleep early, while others tend to sleep late. ![]()
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